Gonadorelin Acetate
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Product Description
【Basic Information】
Gonadorelin Acetate is a synthetic gonadotropin-releasing hormone analogue, a peptide compound composed of 10 amino acids. It regulates the synthesis and release of gonadotropin by specifically binding to the GnRH receptor of the anterior pituitary gland, and is widely used in reproductive medicine and endocrine disease treatment.
【Molecular formula】C₅₅H₇₄N₁₆O₁₃・xC₂H₄O₂
【Molecular weight】About 1182.38 Daltons
【Appearance】White to off-white freeze-dried powder, loose and uniform texture, porous sponge-like, easily soluble in water, clear and transparent solution after reconstitution, no visible impurities.
【Purity】According to HPLC, the purity is ≥98.5%. Through strict quality control process, the impurity content is ensured to be lower than the safety standard, ensuring the activity and stability of the product.
【Core Functions】
1. Regulate reproductive endocrine: through pulse administration, stimulate the pituitary gland to release FSH and LH, promote follicle development, ovulation and sex hormone synthesis, and is often used to treat female hypothalamic amenorrhea, polycystic ovary syndrome, and ovulation induction programs in assisted reproductive technology (such as in vitro fertilization); for men, it can promote the synthesis of testosterone by interstitial cells in the testis and improve reproductive dysfunction such as oligospermia and azoospermia.
2. Treat hormone-dependent diseases: continuous administration can lead to desensitization of pituitary GnRH receptors, inhibit the secretion of FSH and LH, and reduce the production of estrogen and androgen. It is used to treat hormone-dependent diseases such as endometriosis, uterine fibroids, and prostate cancer, reduce the size of lesions and relieve symptoms.
3. Diagnose endocrine function: as a key drug for GnRH stimulation test, by detecting the reaction levels of FSH and LH after medication, it assists in the diagnosis of hypothalamic-pituitary-gonadal axis dysfunction, such as distinguishing true from false precocious puberty and evaluating pituitary reserve function.
4. Research and development purposes: In biomedical research, it is used as a tool drug to explore reproductive endocrine regulation mechanisms, or as an active ingredient to develop new gonadotropin drugs.

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